As stated in the Beta, this patch has not fixed my issue with Desdemona in Underground Undercover. It seems to work for some, but others, besides myself, also noted issues.

I have a fresh install, running no mods, and I've verified the game cache.

No reply about this issue has been forthcoming, but If you are still experiencing this bug, you are not alone. I'd recommend sending a save file in to Bethesda, but I haven't gotten a response even acknowledging they received mine, and I sent it in at the beginning of the Beta, so...

Split from a previous thread that had 3 different platforms being reported in one thread - this one being the posts pertaining to the PC version.