A hunting rifle? I won't do it until I get my hands on Lincoln's Repeater with a bunch of .44 ammo, and have a good stash of Shotgun Shells for my Combat Shotgun.
Lincoln's Repeater is even better than a Hunting Rifle, of course. Its one of the best weapons in the game, though the ammo is much rarer. I don't think that the Hunting Rifle should be underestimated, though - its a staple weapon well up until level 16 or so and is more than adequate for the Those! quest, providing your Small Guns skill is high enough.
Though I love it, I find the Combat Shotgun is almost useless in this quest. The range of the gun is much shorter than the range of your enemies. Much better to pick them off at distance with a Hunting Rifle.
Leave companions behind on this quest, I feel. They get in the way and make sneak attacks almost impossible to get.