I have recently been trying it out and I'm liking it although it does have its downfalls. I like that your Pipboy becomes a more important tool in terms of where you are, how much ammo and health you have and your rads etc.
I dislike how you can't see if you are hidden or not (my first stealth character) but when you encounter enemies it is more of a suprise without the red markers and it is interesting meeting people in the wastes (random encounter) and trying to determine if they are friendly or not.
I like it but I think I may revert back to hud until my next character.
I was wondering whether you have tried or use this gameplay and what your opinion of it is.