In the past I've always been able to play Skyrim with all of my mods perfectly in conjunction with ENBSeries and RealVision ENB installed. I decided to re-install the game and all of the mods, which worked perfectly. However, when I tried to install the wrapper version of ENBSeries, my game instantly crashed when trying to load a save, even if I was starting a new game. I also tried to use the injector version (I remembered to write down skseloader.exe in the ini) and I still had no luck. I then deleted the entire Skyrim folder and installed the game again and repeated the whole procedure but the same thing happened. I've recently installed all of the game DLC which I didn't have while ENBSeries still worked for me, if that helps in any way.