Alright, so I'll start off my saying I'm not great with computers. When I got Skyrim: SE, it was fine. Soon after, I got random crashes to desktop after about 1-5 mins. I'm not sure what is causing it, but I'll put my specs along with my current settings below.

Specs:

Win. 10 64-bit

AMD Phenom II X4 965

NVIDIA GeForce 650 Ti

Corsair Vengeance 8GB RAM

Settings:

1600 x 900 Resolution (16:9 Widescreen AR)

FXAA

(Preset for Low Quality)

Low Shadow Quality

Medium Shadow Distance

No Decal Quality

Low Godray Quality

Screen Space Ambient Occlusion

Lens Flare

Medium View Distance for all

Low Distant Object Detail

Low Object Detail Fade