The game will not start. I can open it from steam or a desktop short cut, the menu (with the options of PLay Support Options and Exit). When I choose play, it'll close and that's it. I've waited a few minutes, restarted my computer, and even uninstalled and reinstalled the game. Any advice?

had the same problem .........but that was dew to missing Microsoft updates (run-time library's & and net framework ext)

do a check integrity of games cache ...............SSE / property's / local files/ games cache ........if there is anything missing this will download it for you

make sure you have the latest Bethesda updates

lastly go to options in the game menu and set it to default (this will detect your video card if it has not done so already) .....if it dose the Detect thingie it will set every thing to Ultra (depending on your card) ...now the game should launch with no problems

and try running the game as a administrator