And I haven't even taken adamantium skeleton which I had planned on. Don't think I'll need it.
That's what I had planned to do as well. You won't need it, trust me. I started with 5 END, took small frame and kamikaze (-2 DT) and I skipped adamantium skeleton. I took toughness as soon as it was available, I also got the DT implant and at level 28 I took toughness again just because nothing else looked good. I just started a new game and took small frame again and have no plans to get A.S.
No, it's on Normal. Maybe I should increase it.
I did, I had to bump the game up to hard by level 12.