I am playing an uber-ninja. With a melee sneak critical I can one shot the majority of the foes in the game. I also have used reverse pickpocketing to insta-kill some muties just for fun. But I found that try as I might - I just cannot one shot a super mutant overlord with a sneak critical. I attempted to reverse pickpocket a grenade for an insta-kill, but it would not let me into his inventory. Anyone else run into this problem and any tips for overpowered sneak criticals - (at least 1000-1500 points of DAM)

Also I have found a pile of bottlecap mines to be cumbersome to use and the terrible combat shotgun to be too loud (alerts everyone in the vicinity)

THere is one Super Mutant Overlord out of the many added in Broken Steel, which they forgot to enable pickpocketting on.
Mod him to make him pickpocketable and have fun being a Psychotic Prankster

Wow... are you mean or what? Picking on them there Muties like that, it's just not right!

Heh, heh...

Give him a face full of Fatman, and you won't need a sneak attack critical.