The FO3 wikia page is rather vague, saying to travel 'on the easten side of the river', but that way there's lots of stuff about wanting you dead. I tried going as the crow flies, but once you get to the eastern side of Greyditch there are invisible barriers stopping you, forcing you to start using the metro. Then all the areas start having their own worldspaces, meaning you can't actualy follow your pipboy anyhow!