God Dammit, I don't think I've ever had such a problem with a game crashing so much! Oblivion wasn't even this bad! It's such an awesome game too, it's really sad that this is probably the third time this week I've come to this forum just to ask a question about crashes.
I seem to have had trouble with almost every DLC crashing, for the exception of Point Lookout and Broken Steel. Granted most of the problems with Zeta and The Pitt somehow ended up fixing themselves, oddly enough, but now I'm trying my hands at Anchorage, and even before my PC gets to go VR, it crashes as soon as (I'm horrible at remembering names) that ass head with the raspy voice talks that woman at the computers.
It always crashes at the exact same time. Mr. Raspy starts yelling at the woman like everything's her fault, then she replies with "What?." After that, poof. I'm staring at my desktop with a crash report engaged. If anybody can help me, I'd much appreciate it. Failing that, a "Ha ha! You're screwed!" reply would also be helpful so I know to just turn my PC's ass around and high tail it.

In case anyone has the same problem, the crash was caused by the unofficial patch mod... The irony... Just uncheck the Anchorage patch esp.