When I play Oblivion all goes well for about 10 mins, then the game decides not to accept any input from my mouse or keyboard and I have to ctrl-alt-del that [censored]. Weird thing is that it isnt an actual "freeze", it i have auto-run on, my guy keeps running and everything else moves along normally as well.

I don't want to have to reinstall Oblivion seeing as with all the mods and [censored] it would take all day. I know what you are thinking, and NO the mods are not to blame as I have had the same mod set up for months and this problem just started very recently.

If anyone else has had this problem please let me know how to fix.

Thank you.

Sounds like you have a peripheral interfering with your control input.

Try changing this line in Oblivion.INI:

bJoystickEnabled=1 to "=0.

Codec Issue. Installed any new software lately?

Try installing the klite basic codec pack. Be sure it is set to repair broken codecs, and ffdshow is set to ignore oblivion, both audio, and video. If you already have the klite pack. Uninstall it, reboot, reinstall it.