» Mon Mar 07, 2011 4:31 pm
Well, of course it's possible, but depennds highly on the difficulty level you play at. If you are on Normal or lower, and you have ok armor and powerful weapons, you'll do much even without stimpaks (with alot stimpaks its IMO too easy, but I recommend keeping 5-10 with always). There's no much insta/fast-killers in the game, you'll have to aware only Deathclaws and Super Mutant Overlords (if Broken Steel installed) and of course Behemoths. Try to avoid traps too (there's no much of them though).
If you play higher than Normal, you'll gonna be VERY skilled player if you're aiming to no-deaths. Especially if you face Deathclaws... it's simply an insta-death without powerful weapon, armor or good sneak skill to sneak out fast. You also have to take a closer look at the environment, everything there could harm you bad or kill you. if you play on this level, I highy recommend to keep Stimpaks with (you can have them alot here, if you face something deadly you don't probably have time to even think about healing when you're dead already).