I just did a new reinstall to try out FWE (its awesome!) But my game seems to be highly unstable for some reason. I CTD around every 5 mins, and right now im stuckt with a CTD when entering the Super Duper Mart. It also seems to CTD when i try to save, sometimes.
My guess is that some of the patches im using arent up to date, because it seems that alot of mods had an update here in April.

Fallout3.esmAnchorage.esmThePitt.esmBrokenSteel.esmPointLookout.esmZeta.esmUnofficial Fallout 3 Patch.esmHairPack.esmCRAFT.esmCALIBR.esmFO3 Wanderers Edition - Main File.esmMart's Mutant Mod.esmRH_IRONSIGHTS.esmUnofficial Fallout 3 Patch - Operation Anchorage.espUnofficial Fallout 3 Patch - The Pitt.espUnofficial Fallout 3 Patch - Broken Steel.espUnofficial Fallout 3 Patch - Point Lookout.espUnofficial Fallout 3 Patch - Mothership Zeta.espDarNifiedUIF3.espCASM.espCRAFT - Activation Perk.espZL-ACR.espxCALIBRmunitions.espSniperZooming.espFO3 Wanderers Edition - Main File.espFO3 Wanderers Edition - DLC Anchorage.espFO3 Wanderers Edition - DLC Broken Steel.espFO3 Wanderers Edition - DLC Mothership Zeta.espFO3 Wanderers Edition - DLC Point Lookout.espFO3 Wanderers Edition - DLC The Pitt.espFO3 Wanderers Edition - UFP Support.espFO3 Wanderers Edition - Followers Enhanced (BrokenSteel).espWeaponModKits.espWeaponModKits - FWE Master Release.espWeaponModKits - OperationAnchorage.espWeaponModKits - ThePitt.espWeaponModKits - BrokenSteel.espWeaponModKits - PointLookout.espWeaponModKits - Zeta.espEVE.espEVE - FWE Master Release.espEVE - FWE Master Release (Follower Enhanced).espEVE Operation Anchorage.espEVE - FWE with WeaponModKits.espEVE Anchorage - FWE DLC Anchorage.espMart's Mutant Mod.espMart's Mutant Mod - DLC Anchorage.espMart's Mutant Mod - DLC The Pitt.espMart's Mutant Mod - DLC Broken Steel.espMart's Mutant Mod - DLC Point Lookout.espMart's Mutant Mod - DLC Zeta.espMart's Mutant Mod - Natural Selection.espMart's Mutant Mod - FWE Master Release.espMart's Mutant Mod - FWE with EVE.espRH_IronSights_Basic_PittPlugin.espRH_IronSights_Basic_PointLookoutPlugin.espRH_IronSights_Basic_VanillaPlugin.espMerged Patch 01.espTotal active plugins: 58Total plugins: 65

You're missing http://www.fallout3nexus.com/downloads/file.php?id=11684 which is required for the Excalibr Munitions shop.

No, somehow it just got disabled when i copied the load order, weird... :shrug:

And then the game wouldt start at all you know