First, my hotkeys stopped working, then I exited the game and tried to load the save, but it doesn't help.
Here is my load order:
Spoiler
Oblivion.esm
CM Partners.esm
Cobl Main.esm
HorseCombatMaster.esm
Unofficial Oblivion Patch.esp
Unofficial Shivering Isles Patch.esp
Knights.esp
DLCShiveringIsles.esp
DLCOrrery.esp
DLCSpellTomes.esp
DLCMehrunesRazor.esp
DLCfrostcrag.esp
Knights - Unofficial Patch.esp
DLCOrrery - Unofficial Patch.esp
DLCMehrunesRazor - Unofficial Patch.esp
DLCSpellTomes - Unofficial Patch.esp
Natural_Habitat_by_Max_Tael.esp
Natural_Vegetation_by_Max_Tael.esp
Natural_Water_by_Max_Tael.esp
Natural_Weather_HDR_by_Max_Tael.esp
Cobl Glue.esp
Cobl Si.esp
Cobl Tweaks.esp
Salmo the Baker, Cobl.esp
Cobl Silent Equip Misc.esp
Real Hunger, Cobl.esp
FF_Real_Thirst.esp
FF_Real_Thirst, Cobl.esp
FrostcragRebornCobl.esp
autosavertest.esp
Oblivion XP.esp
HUD Status Bars.esp
Map Marker Overhaul.esp
Map Marker Overhaul - SI additions.esp
MidasSpells.esp
Synx.esp
ImpeREAL City Unique Districts - All the Districts - Merged.esp
CM Partners.esp
CM Partners Extra NPCs.esp
CM Partners Marker NPCs.esp
CM Partners More NPCs.esp
CM Partners NPC.esp
CM Partners Special NPCs.esp
1em_Vilja.esp
Enhanced Hotkeys.esp
LCD MDMix.esp
SP1stPLegs.esp
RealSleepExtended.esp
Archery Rebalance.esp
Improved Fires and Flames - Increased Sound.esp
DropLitTorchOBSE.esp
Realistic Water.esp
P1DseeYouSleep.esp
Reznod_Mannequin.esp
Oblivion Gate Closer Spell.esp
Bracer.esp
Anduril Reforged.esp
Adonnays Elven Weaponry.esp
PCSoundImoen.esp
HGEC_special_armor_repl.esp
MODRoadRogue.esp
zzEst14r2.esp
test.esp
SupremeMagicka.esp
SM_ShiveringIsles.esp
SM_Scrolls.esp
SM_SigilStone.esp
SM_DLCSpellTome.esp
SM_EnchantStaff.esp
SM_VanillaSpells.esp
Deadly Reflex 6 - Timed Block with no damage or durability changes.esp
Mounted_Spellcasting_Deadly_Reflex_Compatible.esp
DRSplatter.esp
DeadlyReflex 6 - Combat Moves.esp
Oblivion.esm
CM Partners.esm
Cobl Main.esm
HorseCombatMaster.esm
Unofficial Oblivion Patch.esp
Unofficial Shivering Isles Patch.esp
Knights.esp
DLCShiveringIsles.esp
DLCOrrery.esp
DLCSpellTomes.esp
DLCMehrunesRazor.esp
DLCfrostcrag.esp
Knights - Unofficial Patch.esp
DLCOrrery - Unofficial Patch.esp
DLCMehrunesRazor - Unofficial Patch.esp
DLCSpellTomes - Unofficial Patch.esp
Natural_Habitat_by_Max_Tael.esp
Natural_Vegetation_by_Max_Tael.esp
Natural_Water_by_Max_Tael.esp
Natural_Weather_HDR_by_Max_Tael.esp
Cobl Glue.esp
Cobl Si.esp
Cobl Tweaks.esp
Salmo the Baker, Cobl.esp
Cobl Silent Equip Misc.esp
Real Hunger, Cobl.esp
FF_Real_Thirst.esp
FF_Real_Thirst, Cobl.esp
FrostcragRebornCobl.esp
autosavertest.esp
Oblivion XP.esp
HUD Status Bars.esp
Map Marker Overhaul.esp
Map Marker Overhaul - SI additions.esp
MidasSpells.esp
Synx.esp
ImpeREAL City Unique Districts - All the Districts - Merged.esp
CM Partners.esp
CM Partners Extra NPCs.esp
CM Partners Marker NPCs.esp
CM Partners More NPCs.esp
CM Partners NPC.esp
CM Partners Special NPCs.esp
1em_Vilja.esp
Enhanced Hotkeys.esp
LCD MDMix.esp
SP1stPLegs.esp
RealSleepExtended.esp
Archery Rebalance.esp
Improved Fires and Flames - Increased Sound.esp
DropLitTorchOBSE.esp
Realistic Water.esp
P1DseeYouSleep.esp
Reznod_Mannequin.esp
Oblivion Gate Closer Spell.esp
Bracer.esp
Anduril Reforged.esp
Adonnays Elven Weaponry.esp
PCSoundImoen.esp
HGEC_special_armor_repl.esp
MODRoadRogue.esp
zzEst14r2.esp
test.esp
SupremeMagicka.esp
SM_ShiveringIsles.esp
SM_Scrolls.esp
SM_SigilStone.esp
SM_DLCSpellTome.esp
SM_EnchantStaff.esp
SM_VanillaSpells.esp
Deadly Reflex 6 - Timed Block with no damage or durability changes.esp
Mounted_Spellcasting_Deadly_Reflex_Compatible.esp
DRSplatter.esp
DeadlyReflex 6 - Combat Moves.esp
Please help as soon as possible.