Are you setting your mod as the Active File when you load it? Are you getting any error messages (and if so, what do they say)?
My mod is the active mod. I do my changes and SAVE. The CS 'thinks' about it for a while, then; crash to the desktop.
I get a really genero error msg, along the lines of: CS has encountered an error and is shutting down.
Pretty much the same thing I get trying to exit from a well modded game. :shrug: