This game has been unstable for me right from the start, but I've been able to continue up until now, I'm helping ranger grant with the security arrangments, but as he says "gets some rest" first the screen fades to black, then it tries to fade back in at which point I get CTD, I've tried a number of ways to get around this but all fail, I had the same problem with the doc at jacobs place when getting Rex a new brain, since it was not important to the main quest I ignored it then went back later and it worked, but nothing I do will allow me to continue after the discussion with ranger grant, if anyone else has had this problem and knows a fix, please let me know, thanks in advance.
System:
AM3 AMD quad core 3ghz
Memory 4 gig
HD5870 1 gig video memory
(no overclocking)