Anyway, I reinstalled Oblivion a couple months ago, and I've been running it no problem since then. The occasion crash, but nothing to bothersome. Last week, I quick saved and left it paused for a bit when the power went out on the block. I left my computer off for the holiday, and just got back to it today.
Now, it is crashing every few minutes, and after a few reloads, I got the message "This save relies on content that is no longer present..." Only I hadn't changed anything between reloads! I also started a new character to see if that would help, but the second my Altmer started looking good and I actually got a little excited about starting from scratch, it crashed again.
I am running the goty disc on my beast of an hp Blackbird with Windows 7, 2.66ghz quad core cpu, 2gb ram, and ati radeon hd 3870 (my computer seems to be saying there are two of those, if that's a thing). It is installed in my Games folder.
I have every dlc except battlehorn, bab, beautiful women and handsome gents (with improved facial textures and enayla's ft), change your face, harvest containers and flora, intelligence overhaul (though none of those are checked off), leviathan soul gems, quest award leveler, smarter mercantile leveling (which I was to lazy to remove), unique landscapes compilation 1.3.2, and wp health regen. I also use the unofficial patches, though closer inspection shows I do not have the one for Shivering Isles.
I'm hoping I overlooked something really simple, and I won't have to reinstall. It played fine before the power outage. I used to play with a lot more mods, too, but I mostly wanted to do this play through for the lore.