I carry a couple of sets. lvl 51 atm.
I have: (not complete sets in each case, just the elements that support the enchants)
destro/archery
For use when I want to snipe.
destro/regen magicka
My normal setup
destro/magicka
When I really want to use the master level spells (my base magicka pool is less than 700 atm)
destro/alchemy
don't carry this set, just keep it in my house for late night mad scientist activities.
Also, I have sets for the followers I prefer. Complete sets of stuff for Onmund and Areana with enchants for their preferred skills.