Someone figgered out how to get it running? Thanks!

I've heard that D2X-rebirth is supposed to do the job, but I could never figure it out, maybe you could, and let us know how you did it!

You can use D2X-Rebirth or D2X-XL. Both runs pretty well on modern computers and uses 3D Acceleration features.

URL for Rebirth:
http://www.dxx-rebirth.com

URL for D2X-XL:
http://www.descent2.de Visit my website: http://www.pumosoftware.co.nr
and my forums: http://3d-get.de/pumosoft/forum/
There you'll find info about Pumo Mines (my Descent2/D2X-XL mission & mod project)

D1 rebirth works great for me. I even sometimes play over the internet with buddies.

It's already been reported. Makes you wonder why noone has deleted it yet... Moon's Descendarium - THE single-player guide to D1-3
Maintainer of the 'Official' D3 FAQ
DXX-Rebirth: Play D1/D2 on modern PCs