Whenever I leveled up to level 8 I was able to select the Cowboy Perk even though I do not have 45 melee or 45 explosive, the cowboy perk seems to be the only one I can do this with.

Here is my load order:

FalloutNV.esm

DeadMoney.esm

HonestHearts.esm

OldWorldBlues.esm

LonesomeRoad.esm

GunRunnersArsenal.esm

CaravanPack.esm

ClassicPack.esm

MercenaryPack.esm

TribalPack.esm

YUP-Base Game+All DLC.esm

Cinematech.esm

Detect Traps.esm

CCO-Gameplay Changes.esm

Interior Lighting Overhaul-Core.esm

New Vegas Redesigned II.esm

AWorldofPain(Preview).esm

CCO-Follower Tweaks.esm

CCO-Classic Perks.esm

Interior Lighting Overhauil-L38PS.esm

oHUD.esm

Project Nevada-Core.esm

Project Nevada-Equipment.esm

ELECTRO-CITY-Highways and Byways.esm

Project Nevada-Rebalance.esp

Project Nevada - Cyberware.esp

Nevada Skies.esm

SomeguySeries.esm

YUP - NPC Fixes (Base Game + All DLC).esp

DarNifiedUINV.esp

Alternative Repairing - Breakdown Item Icons.esp

DYNAVISION 2 - Dynamic Lens Effect.esp

AWOPLowLootGeneral.esp

pipboy2500_edisleado.esp

ammoingredientsloot.esp

CCO - Perk Rebalance - Dead Money.esp

CASM with MCM.esp

CCO - CP All DLC Patch.esp

CCO - CP PN Patch.esp

ELECTRO-CITY - Imaginator.esp

CCO - CP OWB PN Patch.esp

Project Nevada - Dead Money.esp

Interior Lightning Overhaul - Ultimate Edition.esp

I Got Spurs.esp

CCP - Perk Rebalance - Lonesome Road.esp

CCO - Perk Rebalance - Honest Hearts.esp

LFox Missing Ammo Recipes.esp

CCO - Perk Rebalance - Old World Blues.esp

CCO - Perk Rebalance.esp

EVE FNV - All DLC.esp

Detect Traps - Perk.esp

CCO - FT All DLC Patch.esp

The Mod Configuration Menu.esp

Detect Traps - Traponator 4000.esp

Directors Chair.esp

Project Nevada - Gun Runners Arsenal.esp

LFox Missing Ammo Recipes GRA DLC.esp

Project Nevada - Honest Hearts.esp

CCO - GN PN Rebalance Patch.esp

ILO - A World of Pain.esp

ILO - Nevada Skies Patch.esp

JIP Companions Command & Control.esp

CCO - PR PN Patch.esp

Manual Reload-OldWorldBlues.esp

Manual Reload.esp

My essential friends (animals).esp

AWOP - LowNPCS.esp

NewVegasBounties.esp

ILO - New Vegas Bounties.esp

NewVegasBountiesII.esp

NVR-Recommended.esp

AWOPLowLootMWeaponsArmor.esp

Project Nevada - Lonesome Road.esp

Voice dissonance fix.esp

WeaponModsixpanded.esp

Alternative Repairing.esp

RWD-NV v1.4 [Standard Version].esp

ILO - New Vegas Bounties II.esp

TheInheritance.esp

Russell.esp

WMX-DLCMerged.esp

AWOPDeadMoney.esp

FNV Realistic Wasteland Lighting - Full.esp

Nevada Skies Ultimate DLC Edition.esp

Alternative Repairing - Ultimare Edition.esp

WMX-Arenovalis Textures.esp

Project Nevada - WMX.esp

Project Nevada - EVE All DLC.esp

WMX-AWOP.esp

WMX-EVE-AllDLCMerged.esp

WMX-POPMerged.esp

My Patch.esp

AWOPLowLootSkillBooks.esp

AWOPDeadMoneyVendorPatch.esp

Detect Traps - DLC.esp

ILO - GS Shack.esp

AWOPLowRobots.esp

Alternative Repairing - Additional Campfires.esp

New Vegass redesigned - Honest Hearts.esp

Likely one of your mods that alter perks likely one of the CCO perks plugins.

The original intent of the mod author was to allow the player to either have 45 in explosives or 45 in melee weapons, where as in the vanilla game the Cowboy perk requires 45 in melee weapons.

Ok so I went into FNVedit:

- CCO - Perk Rebalance.esp

-- Perk

--- Cowboy

By reading the tables I notice on the vanilla game, under conditions, it said Greater than or equal to. However on the CCO edits it said Greater than or equal to/OR for Guns, Explosives and Melee. Noticing this I changed all the CCO edits to match the vanilla edits and rebooted a save then leveled to 8 and it fixed my issue, however now it requires me to have 45 in melee weapons and explosives.

Everything is alright now.

I went back into FNVedit and changed the CCO edits for the Cowboy perk to say

Explosives condition to Greater than or equal to/OR

Melee Weapons condition to Greater than or equal to

Guns condition to Greater than or equal to

Reloaded the game, used the console to increase my explosive skill to 45, leveled up and I was able to select the Cowboy perk. ( I did the same thing with melee weapons)

I then reloaded the game and didn't use the command console to edit either skil and was not able to select it.

So all in all, my problem was a simple editing error.

Thanks for your assistance.