1) - The mistrust of magic: Ever since the disaster of Winterhold (I think I have the right place) and the Oblivion Crisis, magic has continually been mistrusted and believed to be evil and not natural.
2) - The doubt of existence of dragons: Whereas Dragons were once fact in Skyrim, over the course of years people have started to believe that they might've just been a myth all along. An archaic, tribal belief that didn't apply to them.
3) - The banning of Talos worship: Because Talos is no longer legally a god according to the Empire (or, at least, his worship is banned by the Empire), we can clearly see that Gods, ever so slowly, are losing their foothold/place among man-kind.
4) - The Mistrust of Mer races: The relationship between Mer and Man is now strained because the White-Gold Concordant Banned Worship for the Empire. Not only are the Altmer mistrusted, but the Dunmer are now slowly earning hatred in Windhelm because of their exodus from Morrowind.
Each of these progresses society in Tamriel towards, if you will, Atheism.
And if the war between the Empire and the Stormcloaks is taken into consideration, you have the extremes of 2 outcomes:
1) - The Empire wins the War. We all know the Thalmor will wage war on man-kind once more and either eradicate them or subject them to their religion and their gods, thus making Tamriel back to it's original state with the Ayleids: Man-kind is enslaved by the Elves.
2) - The Stormcloaks win the war. We can presume here that they will reinstate the Hero worship of Tiber Septim/Talos and, presumably, lead Skyrim into atheism because of their victory over a race that was highly religious and magic-using.
I can reinforce my point with (nearly) dead cultures/religions like those of the Hopi tribe in New Mexico, or (if I dare make too controversial of a comparison), the Jewish religion, who still believe that their god, who is "dead", essentially, but was not always like this and they are waiting for his return to save them. I can also make a game-to-game comparison of Fable 1 vs. Fable 2 where gods and magic was widely accepted and acknowledged, but by the time Fable 2 comes around, magic is a myth.
Either way, it makes for an interesting situation should Bethesda make an Elder Scrolls: VI.
Thoughts/Opinions?