I am needing to get back some of my laptop's memory space and I found that the folder that contains all my downloaded mods is one of the biggest drains on the memory. I use Oblivion Mod Manager to install all of them as steam does not allow them to be installed manually and I am wondering if it would be safe to remove some of the files in that folder if Oblivion Mod Manager has already installed them.
TLDR: Is it safe to delete folders that have been used by Oblivion Mod Manager to install a mod?

Thanks for any help!