Wouldn't most people consider a save that caused a CTD when loading it due to bad data as "corrupted?"
I find it interesting when looking this thread that those who have been around here for years all state they don't rely on quicksaves, and those who are relatively recent additions to our community use them without problems. Significant?
Although the only real tool I had for examining them was Enchanted Editor, I did spend a lot of time comparing saves that couldn't load with other ones. What I usually found was a bunch of extra data in the CELL records that it couldn't identify. By deleting that CELL record, in most cases it would load. That coincides with what john.moonsugar is saying.
When we were having the discussion about whether or not just doing occasional quicksaves improved stability IIRC TP21 played around with his debugger to see if there was any merit to that argument. I don't recall all of the specifics, but he said there was some sort of memory dump that was done before the quicksaves routines that didn't happen before doing a full manual save or autosave.
I for one have always been of the opinion that most save corruption, quick or not, is due to complex scripts. Wrye once postulated that the main difference between the two types of saves is that when you go into the main menu it triggers MenuMode, so most well-written scripts pretty well stop running. Doing a quicksave doesn't do this, so the scripts are saved at whatever state they currently are at.
I have had enough problems, with and without MCP (though I have played far more without honestly,) that I don't use quicksaves. I hardly am inconvenienced by five extra clicks and key presses.