I know it had been said that Loot is going to be randomised to fit what your duder(ette) does which is awesome. I like have random stuff to sell but i really would like useful stuff as well so that sounds great!
But you think there is going to be quest specific items like in older games. IE You save a chicken in a town and no matter what character you do it with you get the pitchfork of chicken saving. Which in turn you sell becasue you have a sword and not pitchforks. Not my best anology but my brain is tired. So is all if not most loot going to be randomized for quests too or just dungeons.

I'm more worried about the opposite problem: the only rewards really worth doing quests for will be set in stone and the randomised quest rewards will be vendor junk. May as well just pay me in cash :shrug:

Edit: Todd said that some quests are set in stone. The only randomised quests will be small, miscellaneous ones and only their location, difficulty, objective and reward will all be randomised. However, most side quests and main quests like FO3's and Oblivion's will have rewards that are the same on every playthrough. So there's a mix.

I do agree with that having some choice would be nice. "You saved my chicken I can either give you my chick pitchfork of saving, or 500 gold.?". That would be pretty sweet. Can't get off the chicken idea still sorry. I just hope there is a reall good balance.

As long as they can make the quests interesting I dont care as much for the rewards.