I tend to CTD after about 2 hrs of play without a warning/error message.
I used boss, tesvedit and created a bashed patch, so it's all fine in the mod departament.
I also have enboost on, yet i crash randomly ?
What is the problem here ?
My pc can easily hande Skyrim (i5-3570k, gtx670)

I don't have this issue with my heavily modded game and 'poorer pc specs'. Post mod load order from BOSS for starters.

What operating system are you using?

Do you run anything like GameBooster to free up resources?

• Skyrim.esm Active
• Update.esm Active
  • Bash Tag suggestion(s): {{BASH: Delev, Relev}}
• Dawnguard.esm Active
  • Bash Tag suggestion(s): {{BASH: Delev, Relev}}
• HearthFires.esm Active
• Dragonborn.esm Active
• Falskaar.esm Active
• ApachiiHair.esm Active
• Skyrim Project Optimization - Full Version.esm Active
• ArmedttTeeth.esm Active
• ClimatesOfTamriel.esm Active
• LevelersTower.esm Active
• WARZONES - Civil Unrest.esm Active
• HighResTexturePack01.esp Active
• HighResTexturePack02.esp Active
• HighResTexturePack03.esp Active
• Unofficial Skyrim Patch.esp Active
  • Bash Tag suggestion(s): {{BASH: Delev, Relev}}
• Unofficial Dawnguard Patch.esp Active
  • Bash Tag suggestion(s): {{BASH: Delev, Relev}}
• Unofficial Hearthfire Patch.esp Active
• Unofficial Dragonborn Patch.esp Active
  • Bash Tag suggestion(s): {{BASH: Delev}}
• Unofficial High Resolution Patch.esp Active
• Bijin Warmaidens CBBE One esp.esp Active
• Chesko_Frostfall.esp Active
• CalienteVanillaArmorTweaks.esp Active
• Chesko_WearableLantern.esp Active
• Immersive Brigands.esp Active
• Immersive Dawnguard.esp Active
• Immersive Factions.esp Active
• Immersive Mercenaries.esp Active
• Immersive Werewolves.esp Active
• DYNAVISION Dynamic Depth of Field.esp Active
  • Note: Make sure you have not switched DoF off in your ini file. If you don't see any effect, open you Skyrimprefs.ini and look for 'bDoDepthOfField'. Make sure it is set to 1.
• Player Size Adjuster.esp Active
• SkyUI.esp Active
• Customizable Camera.esp Active
• BetterArchmagesRobes.esp Active
• Cloaks.esp Active
• 1nivWICCloaks.esp Active
  • Bash Tag suggestion(s): {{BASH: Relev}}
• 1nivWICSkyCloaksPatch.esp Active
• CraftableNightingaleArmor.esp Active
• DaedricAssassinArmorLight.esp Active
• DaedricAssassinArmorHeavy.esp Active
• DaedricCrossbow.esp Active
• Dragon Bone Mage Armor.esp Active
• Insanity's Craftable Dragonbane.esp Active
  • Bash Tag suggestion(s): {{BASH: Deactivate}}
• Insanity's Dragonbane.esp Active
• Insanity's Ice Blade of the Monarch.esp Active
• NightingaleCrossbow.esp Active
• royal_daedric.esp Active
• Tribunal Maskes by Zairaam.esp Active
• Tribunal Robes by Zairaam.esp Active
• Dr_Bandolier.esp Active
• The Paarthurnax Dilemma.esp Active
• FalskaarDawnguard.esp Active
• Headtracking.esp Active
• Magnus100_50.esp Active
• Marriable Serana.esp Active
• masteredmagicka.esp Active
• masteredmagickaenchantmentfix.esp Active
  • Contains dirty edits: 2 ITM, 0 UDR records. Needs http://skyrim.nexusmods.com/mods/25859 cleaning. A cleaning guide is available http://www.creationkit.com/TES5Edit_Cleaning_Guide_-_TES5Edit.
• dD - Enhanced Blood Main.esp Active
• dD-Dragonborn-Dawnguard-EBT Patch.esp Active
• RLO - Adaptive Interiors Vanilla Weathers Patch.esp Active
• RLO - Major City Exteriors - No Guard Torches.esp Active
• ClimatesOfTamriel-Dawnguard-Patch.esp Active
• ClimatesOfTamriel-Dragonborn-Patch.esp Active
• ClimatesOfTamriel Falskaar.esp Active
• ClimatesOfTamriel-Nights-Level-2.esp Active
• wild werewolves.esp Active
• MidasSkyrim.esp Active
  • Warning: Original file was released before the Creation Kit (07 Feb. 2012) an update to the previous compatibility patch fixed and cleaned with TES5Edit can be obtained here. (http://skyrim.nexusmods.com/mods/26230)
• HitStop.esp Active
• Improved Dragon Shouts.esp Active
• Improved Dragon Shouts - Dawnguard.esp Active
• Improved Dragon Shouts - Dragonborn.esp Active
• DeadlySpellImpacts.esp Active
• The Dance of Death - Ultimate Edition.esp Active
• TKDodge.esp Active
• TKRecoil.esp Active
• Vampirelordroyal.esp Active
• Animated Enchantments.esp Active
• Bashed Patch, 0.esp Active

I'm using the compatibility patch for midasSkyrim.esp, and that one dirty file just won't get clean no matter what.
I'm using windows 7 64-bit, and no i'm not using anything like gboost

Enhanced blood is problematic, might want to look up on its problems. Warzones too.

Headtracking runs scripts so fast that it can bog down the engine. Never used it but heavy scriping mods like Headtracking can create stutter, lag, save game bloat and ctd's.

Well if ctd's will happen, i'll just turn some mods off and see if it fixes it.
Thanks for the help guys

You can run the papyrus debugger mode to see what mode is problematic and cause your ctd's actually...