the fact that creatures and factions stick to certain areas makes perfect sense, they would...
However, there are not enough bandit type factions and characters around the map, some areas can be traversed with little to no hostility from as much as a bloat fly... not cool.
A few more members of bandit type factions along the roads and assasination attempts on the courier would solve that though,
I would like more repurcussions from upsetting all of the different factions, but the more grief i've had is from the powder gangers, which lets face it,
from an early level, the courier can punch to death! god forbid you should have a companion with a pistol or better...
I'd like to see something like a version of the talon company or exiled BoS members that are default bad to everyone, who you bump into occasionally,
No reputation with them, just hostility. If you want to have issues with a faction, then you have to go to their secluded base and fight them under their rooves,
and then they're gone from the game, not cool