I'll be the first to admit that as an adamant New Vegas lover I see this as its biggest flaw. No, I don't want it to the degree in Fallout 3, but some variety would be nice. The same 2 powder gangers spawning as some different raiders or wildlife would be good, and more changing of spawns depending on what you do in the game would also be good.
its not that the game needs tons of action in every location 24/4 but there needs to be a random factor in each sector to some degree, so lets say if you're near goodsprings, there would be a possibility of various things that may or may not happen, so that way its not the same 2 bark scorpions in hidden valley or at nipton every single time, one time you may go thru there and find a faction patrol, sometimes maybe two factions in the same area clashing, maybe sometimes a sentry bot, or some super mutants, sometimes nothing, maybe most of the time nothing, each sector needs a certain level of random activity to some degree, even if its super random, but to have it static so that your next playthru is exactly the same is large apsect of the game thats basically broken, RPG's NEED randomness. there is NO excuse to leave a game thats suppose to be an rpg and making it totally static.