And they really are random. The most recent ones were right at the entrance of the broken part of the boat in Rivet City on the way to Pinkerton, I had sat there for a minute waiting for the Mirelurks to come towards me. The other was right as I went to go to the Science Lab.

Here's my load order:

Fallout3.esmAnchorage.esmBrokenSteel.esmZeta.esmThePitt.esmPointLookout.esmFallsChurchMetroFix.esmCRAFT.esmCALIBR.esmCRAFT - Activation Perk.espDarNifiedUIF3.espFOOK2 - Main.esmFOOK2 - [[censored]] World And Neighbourhood Kit.esmFOOK2 - [DIK] DLC Improvement Kit.esmFO3 Wanderers Edition - Main File.esmMart's Mutant Mod.esmDCInteriors_ComboEdition.esmDestruction.esmSharing and Caring Companions.esmStreetLights.esmEnhanced Weather - Rain and Snow.esmEnhanced Weather - Radioactive Rain and Snow Plugin.espEnhanced Weather - Rain and Snow in Fallout.espEnhanced Weather - Weather Sounds in Interiors.espEnhanced Weather - Sneak Bonus during Storms.espFOOK2 - Main.espFellout-BrokenSteel.espFOOK2 - [DIK] DLC Improvement Kit.espFOOK2 - [EVE] Energy Visuals Enhanced.espFOOK2 - Mothership Zeta.espFO3 Wanderers Edition - Main File.espFO3 Wanderers Edition - DLC Anchorage.espFO3 Wanderers Edition - DLC The Pitt.espFO3 Wanderers Edition - DLC Broken Steel.espFO3 Wanderers Edition - DLC Point Lookout.espFO3 Wanderers Edition - Followers Enhanced (BrokenSteel).espFO3 Wanderers Edition - DLC Mothership Zeta.espFO3 Wanderers Edition - Optional Worn Weapons.espFO3 Wanderers Edition - Alternate Travel.espFO3 Wanderers Edition - Followers Enhanced.espFO3 Wanderers Edition - FOOK Support.espFWE - FOOK DLC Support.espWeaponModKits.espWeaponModKits - FWE Master Release.espWeaponModKits - OperationAnchorage.espWeaponModKits - ThePitt.espWeaponModKits - BrokenSteel.espWeaponModKits - PointLookout.espWeaponModKits - Zeta.espDestruction - Main - Statics.espMyFOOK2 - Black & White Tranquility Lane.espMyFOOK2 - No [censored] Victims.espMart's Mutant Mod.espMart's Mutant Mod - DLC Anchorage.espMart's Mutant Mod - DLC The Pitt.espMart's Mutant Mod - DLC Broken Steel.espMart's Mutant Mod - DLC Point Lookout.espMart's Mutant Mod - DLC Zeta.espMart's Mutant Mod - FOOK2.espMart's Mutant Mod - FWE Master Release.espMart's Mutant Mod - Hunting & Looting.espMart's Mutant Mod - Tougher Traders.espWeaponModKits - FWE Optional Worn Weapons.espMart's Mutant Mod - No Wanamingos.espStealth Kills Enabled.espStealth Kills Enabled - Pitt Compatibility.espUPP - Pack 1.espUPP - Pack 2.espRunFaster125percent.espNPCs Sleep Tighter.espSniperZooming.espGeneratorSound.espFalloutFood.espAttentater's Wasteland Economy.espLess Useless Karma Gifts 2.0.espI'll Touch What I Want.espFOOK2 - [DESTRUCTION] Main - Statics.espRegulator Intercom.espMegatonContracts.espCleaned Museum.espCombat Style Perks.espWinchesterRevamped.espGalaxyNewsRadio40[M].espAReasonedArgument.espCanterburyCommonsInteriors.espSunGlassesFX.espFallout Fast Saver v1.0.espMaintenanceShed.espNeunen Fireaxe.espPhalanx-OPTIONAL-BROKENSTEEL-WeaponRepairLists.espPhalanx-OPTIONAL-WeaponRepairLists.espPhalanx-Obedient-Dogmeat.espPhalanx-DogmeatEnemyTweaks.espBuildableBots v0.2d.espRobCo Certified.espFireLightFix.espFireLightFix_rus.espFellout-Full.espFellout-pipboylight.espFellout-Anchorage.espFellout-PointLookout.espFellout-Zeta.espbzBodySuits.espbzArmour-non-nvde.espUnique Dogmeat.espXepha's Dynamic Weather - Main.espXepha's Dynamic Weather - Anchorage.espXepha's Dynamic Weather - Broken Steel.espSCC - Talk to Anyone.espBetter Looking Combat Shotgun.espTotal active plugins: 111Total plugins: 168

I've ben told there are some issues with my mod "DCInteriors" and the "Destruction" mod, I haven't tested it myself. I keep meaning to look into this but, just haven't gotten around to it yet.

try turning one or, the other off and see if you still have problems.

hope this helps.

Cev

Nope, still getting those CTDs. Here's my current load order:

Fallout3.esmAnchorage.esmBrokenSteel.esmZeta.esmThePitt.esmPointLookout.esmDCInteriors_ComboEdition.esmFallsChurchMetroFix.esmCRAFT.esmCALIBR.esmFOOK2 - Main.esmFOOK2 - [[censored]] World And Neighbourhood Kit.esmFOOK2 - [DIK] DLC Improvement Kit.esmFO3 Wanderers Edition - Main File.esmMart's Mutant Mod.esmSharing and Caring Companions.esmStreetLights.esmEnhanced Weather - Rain and Snow.esmCRAFT - Activation Perk.espDarNifiedUIF3.espEnhanced Weather - Radioactive Rain and Snow Plugin.espEnhanced Weather - Rain and Snow in Fallout.espEnhanced Weather - Weather Sounds in Interiors.espEnhanced Weather - Sneak Bonus during Storms.espFOOK2 - Main.espFellout-BrokenSteel.espFOOK2 - [DIK] DLC Improvement Kit.espFOOK2 - [EVE] Energy Visuals Enhanced.espFOOK2 - Mothership Zeta.espFO3 Wanderers Edition - Main File.espFO3 Wanderers Edition - DLC Anchorage.espFO3 Wanderers Edition - DLC The Pitt.espFO3 Wanderers Edition - DLC Broken Steel.espFO3 Wanderers Edition - DLC Point Lookout.espFO3 Wanderers Edition - Followers Enhanced (BrokenSteel).espFO3 Wanderers Edition - DLC Mothership Zeta.espFO3 Wanderers Edition - Optional Worn Weapons.espFO3 Wanderers Edition - Alternate Travel.espFO3 Wanderers Edition - Followers Enhanced.espFO3 Wanderers Edition - FOOK Support.espFWE - FOOK DLC Support.espWeaponModKits.espWeaponModKits - FWE Master Release.espWeaponModKits - OperationAnchorage.espWeaponModKits - ThePitt.espWeaponModKits - BrokenSteel.espWeaponModKits - PointLookout.espWeaponModKits - Zeta.espMyFOOK2 - Black & White Tranquility Lane.espMyFOOK2 - No [censored] Victims.espMart's Mutant Mod.espMart's Mutant Mod - DLC Anchorage.espMart's Mutant Mod - DLC The Pitt.espMart's Mutant Mod - DLC Broken Steel.espMart's Mutant Mod - DLC Point Lookout.espMart's Mutant Mod - DLC Zeta.espMart's Mutant Mod - FOOK2.espMart's Mutant Mod - FWE Master Release.espMart's Mutant Mod - Hunting & Looting.espWeaponModKits - FWE Optional Worn Weapons.espMart's Mutant Mod - No Wanamingos.espStealth Kills Enabled.espStealth Kills Enabled - Pitt Compatibility.espUPP - Pack 1.espUPP - Pack 2.espRunFaster125percent.espNPCs Sleep Tighter.espSniperZooming.espGeneratorSound.espFalloutFood.espAttentater's Wasteland Economy.espLess Useless Karma Gifts 2.0.espI'll Touch What I Want.espRegulator Intercom.espMegatonContracts.espCleaned Museum.espXepha's Dynamic Weather - Main.espXepha's Dynamic Weather - Anchorage.espXepha's Dynamic Weather - Broken Steel.espCombat Style Perks.espWinchesterRevamped.espGalaxyNewsRadio40[M].espAReasonedArgument.espCanterburyCommonsInteriors.espSunGlassesFX.espFallout Fast Saver v1.0.espMaintenanceShed.espNeunen Fireaxe.espSCC - Talk to Anyone.espPhalanx-Obedient-Dogmeat.espPhalanx-DogmeatEnemyTweaks.espBuildableBots v0.2d.espRobCo Certified.espFireLightFix.espFireLightFix_rus.espFellout-Full.espFellout-pipboylight.espFellout-Anchorage.espFellout-PointLookout.espFellout-Zeta.espbzBodySuits.espbzArmour-non-nvde.espUnique Dogmeat.espLeprechauns.espBetter Looking Combat Shotgun.espEssentialCaravan30sec.espA Trail of Crumbs.esp

That load order is a disaster to put it plainly. Open FOMM and hit "Auto sort". It's not perfect, but it works and is an excellent place to start.

Specifically:
1. You're loading ESPs before ESMs. Never do this.
2. You've got Fellout-Brokensteel loading before Fellout-Full. That's going to cause problems, including CTDs.
3. Your compatibility patches are too high. They need to come after ALL the major mods.

Fallout3.esmPointLookout.esmDCInteriors_ComboEdition.esmAnchorage.esmThePitt.esmBrokenSteel.esmZeta.esmFallsChurchMetroFix.esmCRAFT.esmCALIBR.esmStreetLights.esmFOOK2 - Main.esmFOOK2 - [[censored]] World And Neighbourhood Kit.esmFOOK2 - [DIK] DLC Improvement Kit.esmFO3 Wanderers Edition - Main File.esmMart's Mutant Mod.esmSharing and Caring Companions.esmEnhanced Weather - Rain and Snow.esmDarNifiedUIF3.espCRAFT - Activation Perk.espGalaxyNewsRadio40[M].espUPP - Pack 1.espUPP - Pack 2.espRunFaster125percent.espNPCs Sleep Tighter.espEnhanced Weather - Rain and Snow in Fallout.espEnhanced Weather - Radioactive Rain and Snow Plugin.espEnhanced Weather - Weather Sounds in Interiors.espEnhanced Weather - Sneak Bonus during Storms.espFellout-Full.espFellout-Anchorage.espFellout-BrokenSteel.espFellout-PointLookout.espFellout-pipboylight.espAReasonedArgument.espCanterburyCommonsInteriors.espSCC - Talk to Anyone.espPhalanx-Obedient-Dogmeat.espPhalanx-DogmeatEnemyTweaks.espBuildableBots v0.2d.espSniperZooming.espGeneratorSound.espFalloutFood.espMaintenanceShed.espFOOK2 - Main.espFOOK2 - [EVE] Energy Visuals Enhanced.espFOOK2 - [DIK] DLC Improvement Kit.espFOOK2 - Mothership Zeta.espMyFOOK2 - No [censored] Victims.espRegulator Intercom.espMegatonContracts.espFO3 Wanderers Edition - Main File.espFO3 Wanderers Edition - DLC Anchorage.espFO3 Wanderers Edition - DLC Broken Steel.espFO3 Wanderers Edition - DLC Mothership Zeta.espFO3 Wanderers Edition - DLC Point Lookout.espFO3 Wanderers Edition - DLC The Pitt.espFO3 Wanderers Edition - Alternate Travel.espFO3 Wanderers Edition - Followers Enhanced.espFO3 Wanderers Edition - Followers Enhanced (BrokenSteel).espFO3 Wanderers Edition - Optional Worn Weapons.espNeunen Fireaxe.espWeaponModKits.espWeaponModKits - FWE Master Release.espWeaponModKits - OperationAnchorage.espWeaponModKits - ThePitt.espWeaponModKits - BrokenSteel.espWeaponModKits - PointLookout.espWeaponModKits - Zeta.espWeaponModKits - FWE Optional Worn Weapons.espCleaned Museum.espXepha's Dynamic Weather - Main.espXepha's Dynamic Weather - Anchorage.espXepha's Dynamic Weather - Broken Steel.espCombat Style Perks.espWinchesterRevamped.espStealth Kills Enabled.espStealth Kills Enabled - Pitt Compatibility.espMyFOOK2 - Black & White Tranquility Lane.espRobCo Certified.espMart's Mutant Mod.espMart's Mutant Mod - DLC Anchorage.espMart's Mutant Mod - DLC The Pitt.espMart's Mutant Mod - DLC Broken Steel.espMart's Mutant Mod - DLC Point Lookout.espMart's Mutant Mod - DLC Zeta.espMart's Mutant Mod - No Wanamingos.espMart's Mutant Mod - Hunting & Looting.espMart's Mutant Mod - FOOK2.espMart's Mutant Mod - FWE Master Release.espAttentater's Wasteland Economy.espLess Useless Karma Gifts 2.0.espI'll Touch What I Want.espFireLightFix.espFireLightFix_rus.espSunGlassesFX.espFallout Fast Saver v1.0.espFO3 Wanderers Edition - FOOK Support.espFWE - FOOK DLC Support.espFellout-Zeta.espbzBodySuits.espbzArmour-non-nvde.espUnique Dogmeat.espLeprechauns.espBetter Looking Combat Shotgun.espEssentialCaravan30sec.espA Trail of Crumbs.espTotal active plugins: 107Total plugins: 161

Post Auto Sort. Y'think this is better?

Any help here?

FOOK2's DIK requires your DLC's to be in the following order or wires can get figuratively crossed...

[00] Fallout3.esm
[01] Anchorage.esm
[02] ThePitt.esm
[03] BrokenSteel.esm
[04] PointLookout.esm
[05] Zeta.esm

...although that might not have anything to do with your problem.

Well, the Pitt wasn't getting activated so maybe that might help with that problem, but another still remains. Does the new load order look good?

TP would load so long ad DIK was checked, even if your DLC's were out of order. Which LO is "the new" one, 'cause they all still show the DLC's are not in the prescribed order?

Well, the last one. Just ignore the DLCs, I've fixed that.

I'm not familiar and/or don't have many of those plugins, so I guess I can't be of any more help. You might want to just try unchecking a few at a time until you can isolate the cause.

Good luck though.

Well the CTDs happen randomly, so that would take a hell of a long time.

So far so good, but that Pitt problem persists. I have the radio signal, but the quest doesn't appear. Any ideas?

~SetStage 200108C 10 should make it kick in, no matter what.

Alright, I'll try that. Thanks for the help.

Surely you mean 'setstage 0201068c 10'?

Yeah, I figured. It worked, thanks. So far, no CTD.

"DLC01Quest01 "Into The Pitt" [QUST:0200108C]" (FO3Edit)
Does the UK Pitt quest have a different Form ID, 'cause I'm not finding any form in ThePitt.ESM with that ID?
Right on X 2

download BOSS from fallout nexus, it will get your load order sorted out.

I dont know if this will help anyone or not, but I had the same issue the game would crash randomly. Sometimes during a fight other times i would open a door, it would even crash while i was just walking around. At times i could go an hour or two with no crash, other times it would crash 15 min after starting up. At the time I probably averaged about 1 crash per hour, after reading a lot of posts that seemed to be "normal" for a lot of people. After a LOT of disabling and enabling mods I found that Mart's Mutant Mod - Hunting & Looting.esp to be the esp in question. After disabling that I have gone about 11 hours without a crash. I haven't seen anything posted about this causing other people to CTD but disabling it worked for me. I know the esp actually only enables MMMzLooting in the master ESM, but maybe someone that knows a lot more about the mod can take a look and see if there is an issue with one of the looting scripts in Mart's Mutant Mod.esm. It may be an issue with the looting action and one of the other mods conflicting I'm not really sure.