Personally I'd lock to see realtime lockpicking, it'd make stealth much more exciting rather than a case of "exscuse me sir, please can you wait stock still while I pilfer your belongings before you slice my head off with that axe? Ta very much."
totally want this. one of the higher-level stealth perks could slow down time while you're picking locks to mimic MAN I COULD DO THIS IN MY SLEEP.
also this is something i've wanted forever. i don't think it's been confirmed as being in the game, but it would certainly be nice.
ACTUALLY now that i think about it the GI hub update with the tour of the Bethesda offices and the shots of the whiteboard and stuff showed that the player would have an animation playing while crafting things, so maybe stuff like crafting and alchemy and whatnot actually is realtime.