I'm playing with a mouse and keyboard, and always change my movement keys to ESDF (rather than WASD) in first person games. That home-key hand position is far more natural and comfortable for me, and allows access to more hotkeys for games where that matters. In Fallout 4, that setup is causing me some seriously annoying problems, though. I'm constantly either "grabbing" empty corpses and starting to carry them around (using my re-bound "take" key will drop them, though), or looting the first item in a body/container the instant I get within range (before I can even see what said item is), or having my movement abruptly stop if I mouseover something that could have loot in it.
Shouldn't this key switch to the same thing as whatever the player sets their "take" key to? It's really driving me nuts, and I'm not even very far into the game yet.