Regarding endings - on my first char I sided with the Brotherhood but blew up the Institute with the Minutemen, as the Brotherhood were starting to rather annoy my char, the business with Danse and the Railroad was a step too far..
What do I have available in terms of faction content? I mean, do I still have, for example, radiant quests with the Brotherhood? Or story content? I'd be a little pissed if siding with the Minutemen right at the end meant that the only repeatable content came from Preston...