In case a player decides to replay to try a different approach, perhaps the game could recognize that it is a replay and make some stuff easier:

- For example after looting a settlement, perhaps there could be a store all junk items in the workbench and scrap the rest.

- Mark two settlement corners and build a wooden wall between them (to quickly fence the whole thing again)

- Perhaps the game could even recommend trying a different approach at some changes in game.

Edit: Of course if the game was really really over-dynamic that would be replaying all the time.