Wondering if anyone can help out with this, I know there was one at one time in F3. If this is not available could someone point me in the right direction on how to accomplish this? I;ve used mods before but no so good on the SE. Much appreciated

To do this, you'd need to use NVSE's http://fose.silverlock.org/fose_command_doc.html#GetHotkeyItem to check which items are being referenced by the various hotkeys, and its http://fose.silverlock.org/fose_command_doc.html#IsKeyPressed to detect when the mouse wheel is being used (scancodes 264 and 265 for up and down, respectively).

Equipping/unequipping the items could be done via either http://geck.gamesas.com/index.php/EquipItem/http://geck.gamesas.com/index.php/UnequipItem, or by using NVSE's http://fose.silverlock.org/fose_command_doc.html#TapKey to emulate the relevant hotkey being tapped.

Cipscis

I was never able to get the dang mouse wheel to stop moving the camera in and out in Fallout 3. Without that scrolling through the hotkeys will be problematic. You'd probably have to exclude hotkey 2 as well.

If anyone knows how to stop that behaviour I'd appreciate it. Then maybe we could port over the hotkey scrollers from Oblivion and it would be even better.

Unfortunately, FVSE's DisableKey doesn't seem to work with mouse wheels, so that doesn't work (and even if it did, IsKeyPressed wouldn't return 'true' if the wheel was disabled and you tried using it). Gonna have to ask for some new functions from the NVSE team to get it working if we can't find some other way to disable the scroll wheel zooming in/out.

There was a setting in vanilla Oblivion that would change the scroll distance to zero, but that setting was eliminated for Fallout and none of the similar settings seem to work.

Well I've never had the problem of the wheel functioning alone, or zooming in and out for that matter. But i did appreciate the mod in F3. Made it easier to hit the 3 -4 weapons I use the most. I did have one for oblivion as well, I remember scrolling through my spells with it. Oh well I'll check back, surely someone will figure something out. Thanx for all the work a lot of you do btw