It is possible to create "empty" responses with SKSE's localization. Make the text/subtitle part of the response into a unique string that will then be replaced by an empty string via a text file in \Skyrim\Data\Interface\Translations\MODNAME_LANGUAGE.txt. The text file should contain the unique string and the empty string, but separated by a tab.
I use a bunch of these for the menu of the crafting services feature. Each topic is an option and each empty response is there to do stuff in the script fragment. The response is "$ILMA_InvisibleDialogue" and the translation file contains "$ILMA_InvisibleDialogue " (that space at the end is actually a tab).
https://github.com/schlangster/skyui/wiki/MCM-Advanced-Features#wiki-Localization