I checked FO3Edit and only one mod affects two of them, Hairday.esm. Nothing is touching their AI packages. ResetAI does nothing, and disable / enable doesn't shake them. It would be nice to see them go back to their lives. Disabling mods one by one might find the culprit, but man I've done this so many times.
Is there a console command or workaround to get them back on their schedules, or anything I can try? At least I heard new dialogue: Trinnie asking Brock why he never hits on her.