Will we finally see traders, travelling NPCs, travelling groups, escorts, adventurers, guard posts and all the nifty things modded into Oblivion, along with the occasional Imperial patrols?
Things that modders couldn't get to work properly were caravans, carts and carriages. Maybe they could take a hint from Red Dead Redemption and allow you to pay for a scenic ride as an alternative to fast travel?
Well roads will be empty often like it is in real life for medieval times but your completely right, the npcs you listed definitely need to travel the roads. From the snippets of information about how advanced the Radiant AI system is in Skyrim, I'm sure they have some system in place that has NPCs following the roads for meaningful reasons other than just to do it. Oblivion had a few npcs that would travel the roads to get to another town because they had to do things like the Khajiit from anvil, the wood elf that you have to kill for the Dark Brotherhood quests and the Countess (don't remember which town)
how about random encounters? It was one of the things I really liked in FO3 and it wouldn't look out of place in a TES game, I reckon.
Random encounters have been confirmed.