Picture this: You have a lot of loot, and you need some place to stash that loot, maybe even organize it, and chill, but you don't want to have a house in town... So you have a little cabin in the forest, or a cave, or an underground hidden hobbit-style house that you built yourself or found or liberated from bandits, and that you can upgrade with generic furniture (bed, weapon rack, potion and food storage, crafting ingredient bins, etc) purchased from a furniture store in town, or crafted by yourself. This is your base of operations, etc. You may have one or two safehouses or maybe a few scattered across the map, etc.
By generic furniture I mean that you don't have to go to a specific person to purchase the furniture for your specific house, the store exists as a furniture store and has multiple styles of furniture etc.
Anyways, even if you own a home in town, your safehouses can be a home away from home in other parts of the country, etc.