So it has started again my CTD woes, so let me give a break down

Cambridge police station - Can not move past Polymer labs or it CTD more or less 65foot in all directions. This has been since the first patch.

Goodneighbor - Can not exit via door or fast travel out, coc does also not work, was able to go in and out but all of a sudden this has started again.

Fast Travel - From any where to any where, did the listening station bravo console thing. Also the enable layers code

Random - More frequently since patch within 5 minutes from launching game.

Did the opt out of beta and a roll back with the whole verify cache thing. CTD still continues even on a new profile.

Only mods im running are texture and most are in the scope of Vivid landscapes or DDproductions, any Armor mods are not over 2k.

Game was actually working great till they add the loading time patch and that is what seems to of stuffed me up.

As I said I have opted out of beta but all issues now remain.

You should ask for this to be put in the PC Software Issues forum so you could get more help.

You will need to provide a dxdiag.txt in spoiler tags and a mod list too.

"Only mods im running are..."
LoL, heheh - I stopped reading right there!
You need to get the bone-stock, original game running well.
(In ~200 hours I personally have not seen one crash, NOT ONE.)
And it has nothing to do with "patches"...
The game works perfectly, just the way Beth delivered it. Try playing it that way!
If you still have issues then post them in the PC hardware forum.