So I finally beat FNV for the first time (late to the party much?)

I was thinking what to do for my second playthrough. Should I play on hardcoe this time?

I want to use different skills etc. In this recent playthrough I went with Lockpick, Guns, Repair and Speech and if I used the same again I could see the game get boring quickly. So, any suggestions on what skills I should pursue? I want to use a different weapon type but judging by my first playthrough guns are a pretty big part
of the game. I would also like to side with a different faction, after siding with Mr. House in my 1st playthrough.

And also a question to have somewhat of a discussion point - do you guys like to mix it up when relaying through FNV, or just stick with the same old?

Go hardcoe, energy weapons, Legion, anti-NCR, anti-House, and chose a different gender.