This is my first play through of this game. Do you think I should get the skill points? I could use them on two-handed and enchanting. What do you suggest?
My Opinion,
If You have found swinging Two Handers to be more fun than One-Handed, then go ahead. I Legendarize Conjuration at least twice on (most of) My Mages. I do have a Saved Game from a character that took the Weapon specific Perks in One-Handed, and will spend Friday Night exploring Solsthiem to free up the Five Perks.
I would not Legendarize a Skill that takes a long time to relevel, or a Skill that is really needed by My character. I have Legendarized Destruction on a Mage, because I wanted to face the Ebony Warrior with a Pure Mage. I would not Legendarize Conjuration on My Necromancers, Thralls need to be replaced sometimes.
I'm not sure why you invested in both one-handed and two-handed skills. Perhaps you want the ultimate melee fighter? It might be a good idea to take the perk points out of one-handed and invest in combat skills such as Block, Heavy Armor, Light Armor, and even Sneak or Archery. This way, you'll have a more robust fighter who can hide, deal damage from a distance, and handle close-quarter fights as needed. Good luck!
I never reset offensive skills, but thats just me. Then again, if your two-handed is at 69 you can use those perk points there so it shouldn't be too bad. I'd say go for it.