I completed the quest and got Mehrune's Razor a long time ago. It has been hundreds of in-game days since I killed the four dremora there. They have not spawned once since then. All of the items, chests, etc. spawn normally, but the dremora are nowhere to be seen. Obviously, the dremora are the most important part, as this is the best place in the game to collect daedra hearts. I need these daedra hearts, so it this is very frustrating for me. It seems that this should be an easy glitch to fix, so I have been patient in waiting for a patch, but this has not yet been fixed.

Has anyone else been experiencing similar problems? I have read that other people have had spawning issues at the Shrine as well.

I might be wrong but I don't think they're suppose to respawn. Atleast they haven't for me even back in November. I know someone at the college of winterhold sells them though.

No, they should respawn. That's what makes this such a valuable place. And yes, I will be going to the College to get daedra hearts. However, it would be nice if I could simply get them for free in quantity as I should.

yeah I found some vendors selling those daedra hearts as well. two as far as I discovered. One in Whiterun ( the alchemy vendor) and the other in Windhelm also a Alchemy vendor... because its rare they dont have it standard. you might have to wait a couple days and return. They also sell those giant toe.. but because its rare as well they dont have it every time. Goodluck

They used to respwan about every 72 hours. I can no longer get them to show up either.

the two outside by the alter dont respawn, they never did, the are only spawned for the quest and your 'final test' if you kill the other guy, or to kill you and the other guy if you choose to let him live, if you choose to let him live they will chase the other guy down and attempt to kill him first before attacking you, the only way that they would respawn is if the quest was glitched and you never really finished it. The two daedra inside I really dont know about, i've never gone back inside after finishing the quest.

If you need daedra hearts you can buy them at the winterhold college, every 72 hours you can buy 2 there.

The ones in the inside were the ones that respawned. For some reason they won't anymore.

Yeah, I've just been buying from vendors. Still it's annoying that the dremora won't respawn :/