i have the same proble. After some deaths, i reload the checkpoint and melee is completely gone. No matter what key you bind it too. only solution i found was to quit game and restart.
I had that problem also. If there any of the little alien bugs (no pun intended) running around on the floor and you get close enough to squash them, your melee should be magically re-enabled.
Me too,everytime I died,I must quit the game and restart it to make the melee work properly. And when I finally played through the whole SP,I'm frustrated to find there're much more bugs in MP.T T