Well, playing on an Ipad 2, have 46 Dwellers and lots of rooms. It would crash about 75% of the time when loading my vault, but it would eventually load in and i could play. If i kept it zoomed out all the way (no animations), the game would run alot better with very few mid-game crashes. Well, i decided to push for 50 Dwellers so i could unlock the Game Room (Luck is a big boost to basically everyone). Male and Female started dancing in the Living Quarters, then just as they were about to go into the bedroom and have six, the game zoomed all the way in, and crashed. Now that vault won't load up at all, even after 50+ attempts.

Luckily, i had recalled Star Paladin Cross from the Wasteland shortly before that, and i'm a patient person so haven't paid for any lunch boxes. Not going to delete that Vault, i'll just wait for Bethesda to release more patches. Hopefully they release a patch that allows you to configure the settings, like turning animations on or off. I think that would help alot of people with their crashes.