I've read Todd mentioning that the three weapon categories will be One-Handed, Two-Handed and Bow. Hand to Hand likely won't get it's own skill, it will probably be included in the Two-Handed category.
I heard or read that as well, and the lack of mention of Hand-to-Hand in the context of
that discussion is precisely why I have some doubts about the inclusion of Hand-to-Hand.
The very foundation of TES is that you get better at something the more you do it. Only way they could not include it as a skill is if they physically do not allow us to swing our fists. How could they explain that when we having nothing equipped? That would be completely jarring.
I have come to exactly the same conclusion. But they did remove Acrobatics and Athletics, so the removal of Hand-to-Hand is certainly possible.
It's not a leap of logic to assume that hand to hand is considered a two-handed weapon, unless of course you plan on fighting with one arm tied behind your back. So you use that style, your 2Handed skill goes up, and a perk becomes available that applies to Unarmed combat.
But why would two handed skill go up when you're fighting with a sword in one hand and punching things in the other?
Fighting with fists is
nothing like fighting with something so big and heavy that it requires both hands. And, having only one hand equipped does appear to be an option.