When duel wielding, do you think there will be a dominant hand that does more damage?
I can't say with any certain but I'm guessing no. The combat is supposed to be more "brutal" so it seems more than in Morrowind and Oblivion, you'll need to use both arms for doing something instead of "I have a shield and sword but I almost never raise my shield because it is easier to just kill them faster and just take the weak attacks to my heavy armor.
their will be no multiplayer, right?
They haven't mentioned anything about it. I know of a lot of people that want multiplayer. I for one prefer singleplayer but if I could get an MMO version of TES where it takes place in all of Tamriel's land and is exactly like the TES games (No hotkeyed abilities like WoW and every quest, the main stream MMOs). I love to be working for the Dark Brotherhood and assassinate other players that murdered some player or murdered an NPC and the family of that NPC hires the Dark Brotherhood or Morag Tong to assassinate the player. Mainly I would only like a dynamic, MMO version of TES if it was a hardcoe server in which if you died, you died. That would be fun. Hell I think I'm going to mod that into Skyrim if they give us a construction set. Now to find me a server.