That is the interface to enable whatever mods you put into your Data/ folder.
When you start using mods, you'll see!
(however, in reality you will probably use a mod managed to load 'fomods' like Fallout 3/Oblivion etc)
The checked files you see there currently is the main Skyrim '.esm' file. A mod is similar, and just loads content into the game world by checking it.