Fallout 3's UI was, better... but it was still very tedious. The fonts were still too large, the UI took way more space than it needed to. The DarNified UI for Fallout 3 was much better concerning space.
I will concede that there was room for improvement, as many things do (now that you mention it I may check out the mod!). But we have seen an inprovement, so I'm fairly confident that they'll go one step further with Skyrim. And to be honest, the only reason I went into my inventory in ESIV or FO3 was to heal, repair, change armour or quickslot loadouts. Most of the time I used the quick slots. That may be why the UI never bothered me.
Needless to say, I'm looking forward to seeing how they've changed it.