Does anyone know why I'm not able to to do any upgrading or enchanting. I'm at lvl 42, with a Smithing lvl of 93. All of a sudden I click on the use button and nothing happens. I tried in different locations,and checked my inventory, nothing stolen, and no negative effects on me. I had used them dozens of times before.

Only the gods can smite...

Do you mean Arcane Enchanters and Smith forges, grindstone, workbenches and tanning frames wont work? Did you join the Brotherhood by any chance?

No i have not joined the brotherhood yet, only the companions, which gave me 100% warewolf blood. And yes I mean forges, workbenches etc.