Nope. Developers put multiplayer in single player franchises because publishers try to pull in the stupid Call of Duty fanbase. They think "hey, if we cram multiplayer into this game that doesn't need it, then the kids and dudebros that buy games and never even play the campaigns if they have them will buy our game too!"
You go look up pretty much any forum or reddit post about multiplayer in traditionally single-player franchises and you'll usually get a resounding "no." by the members of those respective communities.
And while it is a small sample size, it's definitely foolish to assume that the non-posting majority thinks any differently, especially when there's no actual data to back up that claim. Occam's Razor applies.
Also, what Todd Howard said is irrelevant, really. He's never said anything like "Our hearts are set on not including dragons in our games." However, he HAS said "Our hearts are with the single-player experience." The fact that they "got one of them this time" in no way implies they'll ever get the other.