I have Streamline installed and it will not run. I use the Alternate Start mod and was wondering if that was causing it not to start?

An alternative start mod should not affect it. Post your load order and you'll get more/better help.

Oblivion.esm
All Natural Base.esm
Oscuro's_Oblivion_Overhaul.esm
Armamentarium.esm
Better Cities Resources.esm
Unofficial Oblivion Patch.esp
Oblivion Citadel Door Fix.esp
DLCShiveringIsles.esp
Unofficial Shivering Isles Patch.esp
Better Cities .esp
All Natural.esp
All Natural - SI.esp
OBGE - Liquid Water.esp
All Natural - Real Lights.esp
Enhanced Economy.esp
DynamicLeveledLists.esp
Streamline 3.1.esp
Dynamic Map.esp
DLCHorseArmor.esp
DLCHorseArmor - Unofficial Patch.esp
DLCOrrery.esp
DLCOrrery - Unofficial Patch.esp
DLCVileLair.esp
DLCVileLair - Unofficial Patch.esp
DLCMehrunesRazor.esp
DLCMehrunesRazor - Unofficial Patch.esp
DLCSpellTomes.esp
Horse Management.esp
Weapon Expansion Pack for Oblivion Nthusiasts.esp
DLCThievesDen.esp
DLCThievesDen - Unofficial Patch.esp
DLCThievesDen - Unofficial Patch - SSSB.esp
Oscuro's_Oblivion_Overhaul.esp
OMOBS_SI.esp
ArmamentariumArtifacts.esp
DLCFrostcrag.esp
DLCFrostcrag - Unofficial Patch.esp
Knights.esp
Knights - Unofficial Patch.esp
xuldarkforest.esp
xulStendarrValley.esp
xulTheHeath.esp
XulEntiusGorge.esp
xulFallenleafEverglade.esp
xulColovianHighlands_EV.esp
xulChorrolHinterland.esp
xulBeachesOfCyrodiilLostCoast.esp
xulBravilBarrowfields.esp
xulLushWoodlands.esp
xulAncientYews.esp
xulAncientRedwoods.esp
xulCloudtopMountains.esp
xulArriusCreek.esp
xulPatch_AY_AC.esp
xulRollingHills_EV_withoutWheat.esp
xulPantherRiver.esp
xulRiverEthe.esp
xulBrenaRiverRavine.esp
xulImperialIsle.esp
xulBlackwoodForest.esp
xulCheydinhalFalls.esp
xulAspenWood.esp
xulSkingradOutskirts.esp
xulSnowdale.esp
OOO-Snowdale Patch.esp
xulCliffsOfAnvil.esp
OOOCliffsofAnvilPatch.esp
xulSilverfishRiverValley.esp
Harvest [Flora].esp
Harvest [Flora] - DLCFrostcrag.esp
Alternative Beginnings.esp
RshAlchemy.esp
RenGuardOverhaul.esp
JCN_AV Uncap.esp
Sneaking Detection Recalibrated.esp
Better Cities Full.esp
Better Cities - VWD of the IC.esp
Better Imperial City.esp
Better Cities Full FPS Patch.esp
Better Cities - Unique Landscape Barrowfields.esp
Better Cities - Unique Landscape Chorrol Hinterland.esp
Better Cities - Unique Landscape Cheydinhal Falls.esp
Better Cities - Unique Landscape Skingrad Outskirts.esp
Better Imperial City FPS Patch.esp
Better Cities - Unique Landscape Imperial Isle.esp
Better Cities - No LEYAWIIN Flooding.esp
Duke Patricks - Combat Magic II.esp
Bashed Patch, 0.esp

http://tescosi.com/wiki/Oblivion:How_to_Post_Your_Load_Order#Using_Wrye_Bash (try the Wrye Bash method - more info is conveyed, that way).

Is Streamline patched? Have you run the latest version of BOSS, and done whatever it recommended you do?

A minor (unrelated) thing - you don't need the Oblivion Citadel Door Fix.esp plugin. Except if it turns out that you do, in which case, maybe add it in then.

Also, have you installed Oblivion in the default directory, and are you also using Windows 7 or Vista? If so, uninstall Oblivion and reinstall it somewhere else, like say, C:\Games\Oblivion (just for example).

And what OBSE plugins are you using?


edit: I use the same alt start mod, along with Streamline, and they seem to be quite happy to work together...

Uhm, are you sure its not working. In game, try pressing your right Ctrl key and Home key together, if its working thats the key combination for streamlines in game menu.